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ORGANIC CHEMISTRY BY DR ANTHONY · 4W ago

NOESY experiment of diastereomer 10α (3S, 5R) …….(3S,5R)-3-Benzyl-5-isobutyl-1,3,4,5-tetrahydro-2H-thieno[3,2-e]- [1,4]diazepin-2-one (10α)

NOESY experiment of diastereomer 10α (3S, 5R) (3S,5R)-3-Benzyl-5-isobutyl-1,3,4,5-tetrahydro-2H-thieno[3,2-e]- [1,4]diazepin-2-one (10α): Pale yellow solid, 50% (64.0 mg), m.p. 66.7–67.4 °C....
ORGANIC CHEMISTRY BY DR ANTHONY · 1M ago

trans-2-(benzo[d][1,3]dioxol-5-yl)-2-methylcyclopropane-1-carbonitrile

trans-2-(benzo[d][1,3]dioxol-5-yl)-2-methylcyclopropane-1-carbonitrile yellowish solid (53 mg, 66%); m.p. = 72 °C; 1 H-NMR (600 MHz, CDCl3): δ = 6.77 – 6.71 (m, 3H), 5.94 (s, 2H), 1.63 – 1.5...
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

2-{[6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl}-4-fluorobenzonitrile

2-{[6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl}-4-fluorobenzonitrile (4) white solid . Mp: 193–195 °C. 1H NMR (400 MHz, CDCl3) δ (ppm): 7.74–7.76(m, 1H), 7.14–7.17 (m, ...
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

NEW DRUG APPROVALS BLOG HITS 16 LAKH VIEWS IN 213 COUNTRIES

Originally posted on New Drug Approvals: NEW DRUG APPROVALS BLOG HITS 16 LAKH VIEWS IN 213 COUNTRIES
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

Efficient synthesis of isoquinolines in water by a Pd-catalyzed tandem reaction of functionalized alkylnitriles with arylboronic acids

Efficient synthesis of isoquinolines in water by a Pd-catalyzed tandem reaction of functionalized alkylnitriles with arylboronic acids Green Chem., 2017, Advance Article DOI: 10.1039/C7GC002...
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

Resolution of Thiele’s acid

Resolution of Thiele’s acid Jun Chen,a XuXin Sun,a Allen G. Oliver,b Jeremy E. Wulffa aDepartment of Chemistry, University of Victoria, P.O. Box 3065 STN CSC, Victoria, BC V8W 3V6, Canada. b...
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

Award for me, 100 Most Impactful Health care Leaders, Global listing

Originally posted on New Drug Approvals: At award function for my award “100 Most Impactful Health care Leaders Global listing”, conferred on me at Taj lands end, Mumbai, India on 14 Feb 201...
ORGANIC CHEMISTRY BY DR ANTHONY · 3M ago

A Brønsted acid catalysed enantioselective Biginelli reaction

A Bronsted acid catalysed enantioselective Biginelli reaction Green Chem., 2017, Advance Article DOI: 10.1039/C6GC03274E, Paper Margherita Barbero, Silvano Cadamuro, Stefano Dughera A chiral...
ORGANIC CHEMISTRY BY DR ANTHONY · 3M ago

Highly chemoselective reduction of nitroarenes over non-noble metal nickel-molybdenum oxide catalysts

Highly chemoselective reduction of nitroarenes over non-noble metal nickel-molybdenum oxide catalysts Green Chem., 2017, 19,809-815 DOI: 10.1039/C6GC03141B, Paper Haigen Huang, Xueguang Wang...
ORGANIC CHEMISTRY BY DR ANTHONY · 3M ago

Synthesis of tetrazines from gem-difluoroalkenes under aerobic conditions at room temperature

Synthesis of tetrazines from gem-difluoroalkenes under aerobic conditions at room temperature Green Chem., 2017, Advance Article DOI: 10.1039/C6GC03494B, Paper Zheng Fang, Wen-Li Hu, De-Yong...