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ORGANIC CHEMISTRY BY DR ANTHONY · 1W ago

Besifovir, бесифовир , بيسيفوفير , 贝西福韦 ,

Originally posted on New Drug Approvals: Besifovir Molecular FormulaC10H14N5O4P Average mass299.223 Da UNII-4PLG22CQUU Phosphonic acid, [[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]me...
ORGANIC CHEMISTRY BY DR ANTHONY · 1W ago

Design, synthesis and biological evaluation of novel 5-hydroxy-2-methyl-4H-pyran-4-one derivatives as antiglioma agents

Originally posted on New Drug Approvals: Design, synthesis and biological evaluation of novel 5-hydroxy-2-methyl-4H-pyran-4-one derivatives as antiglioma agents Med. Chem. Commun., 2018, Adv...
ORGANIC CHEMISTRY BY DR ANTHONY · 2M ago

LL 3858, SUDOTERB

Originally posted on New Drug Approvals: LL 3858, SUDOTERB UNII-SK2537665A; CAS 676266-31-2; N-[2-methyl-5-phenyl-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]pyrrol-1-yl]pyridine-...
ORGANIC CHEMISTRY BY DR ANTHONY · 3M ago

NNC 45-0781

Originally posted on New Drug Approvals: NNC 45-0781 Molecular Formula C27H29NO3 Molecular Weight 415.5241 CAS 207277-66-5 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)...
ORGANIC CHEMISTRY BY DR ANTHONY · 4M ago

Ethyl(1R,2S,3S,4S)-2-(furan-2-yl)-3-nitro-6-oxobicyclo[2.2.2]octane-1-carboxylate

Ethyl(1R,2S,3S,4S)-2-(furan-2-yl)-3-nitro-6-oxobicyclo[2.2.2]octane-1-carboxylate Compound 7 Ethyl(1R,2S,3S,4S)-2-(furan-2-yl)-3-nitro-6-oxobicyclo[2.2.2]octane-1-carboxylate To a solution o...
ORGANIC CHEMISTRY BY DR ANTHONY · 4M ago

Synthesis of isosorbide: an overview of challenging reactions

Originally posted on New Drug Approvals: Synthesis of isosorbide: an overview of challenging reactions Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01912B, Tutorial Review C. Dussenne...
ORGANIC CHEMISTRY BY DR ANTHONY · 4M ago

ELAMIPRETIDE

Originally posted on New Drug Approvals: Elamipretide H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2 D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-...
ORGANIC CHEMISTRY BY DR ANTHONY · 4M ago

Total CCl4 guest alignment in a quasiracemic clathrate closely related to Dianin’s compound

Total CCl4 guest alignment in a quasiracemic clathrate closely related to Dianin’s compound CrystEngComm, 2017, 19,5703-5706 DOI: 10.1039/C7CE01275F, Communication Christopher S. Frampton, J...
ORGANIC CHEMISTRY BY DR ANTHONY · 5M ago

2,5-Bis(ethoxymethyl)furan

2,5-Bis(ethoxymethyl)furan, 6 1H NMR (CDCl3) = 6.20 (s, 2H), 4.36 (s, 4H), 3.47 (q, 4H, J = 7.1 Hz), 1.16 (t, 6H, J = 7.1 Hz); 13C NMR (CDCl3) = 150.9, 109.7, 65.7, 64.7, 15.1 ppm PREDICTS E...
ORGANIC CHEMISTRY BY DR ANTHONY · 5M ago

TOZADENANT

Originally posted on New Drug Approvals: Tozadenant RO-449351 SYN-115 Molecular Formula C19H26N4O4S Average mass 406.499 Da A2 (3); A2a-(3); RO4494351; RO4494351-000; RO4494351-002; SYN-115 ...